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ηγωεϊ εδεγςεϊ μςιϊεπεϊ

θας ε-Active Biotech ιεφΰεϊ μπιρει ωμα 3 αϊψετϊ δ-Laquinimod , θιτεμ ΰεψΰμι αθψωϊ πτεφδ

07/06/2007 ζΰϊ μΰηψ δφμηϊ δωμα δωπι ωμ δπιρει αϊψετδ, ωδψΰδ δτηϊδ ατςιμεϊ δγμχϊιϊ αξεη εαωιςεψ δδϊχτιν ωμ ηεμι θψωϊ πτεφδ αωμα δδϊχτι (RRMS), ΰωψ πθμε ΰϊ δϊψετδ αξιπεο ωμ 0.6 ξ"β ξγι ιεν αξωκ 36 ωαεςεϊ

ιψεωμιν, ιωψΰμ εμεπγ, ωεεγιδ (7 αιεπι 2007) - θας ϊςωιεϊ τψξφαθιεϊ ας"ξ (πΰργ"χ: TEVA) εηαψϊ Active Biotech AB δωαγιϊ (OMX NORDIC: ACTI) δεγιςε διεν ςμ λπιρδ μωμα δωμιωι ωμ δπιρει δχμιπι αϊψετϊ Laquinimod - ϊψλεαϊ ηγωπιϊ μθιτεμ αηεμι θψωϊ πτεφδ αωμα δδϊχτι (RRMS) αξϊο γψκ δτδ, ςμ αριρ ιεξι.

δξςαψ μωμα 3 αΰ αςχαεϊ ριεξε δξεφμη ωμ δπιρει αωμα 2 εςν ϊεν δγιεπιν ςν ψωεϊ δξζεο εδϊψετεϊ δΰξψιχΰιϊ (δ-FDA) εψωεϊ δϊψετεϊ δΰιψετιϊ (δ-EMEA).

αξρβψϊ δωμα δωμιωι ϊαφςπδ δηαψεϊ ωπι πιρειιν χμιπιιν βμεαμιιν ωμα 3 . δπιρειιν, ωιϊηιμε ςεγ δωπδ, ιϊχιιξε αΰψδ"α, αΰιψετδ εαξχεξεϊ περτιν αψηαι δςεμν.

"δωμα δωμιωι ξδεεδ ΰαο γψκ ηωεαδ ατιϊεη ϊψετδ ωϊφις θιτεμ ημετι πεη ιεϊψ ςαεψ ηεμι θψωϊ πτεφδ λημχ ξδξηειαεϊ ωμ θας μξφεΰ θιτεμιν δξφιςιν ψξδ βαεδδ ωμ ιςιμεϊ εαθιηεϊ ", ΰξψ ωμξδ ιπΰι, πωιΰ εξπλ"μ θας ϊςωιεϊ τψξφαθιεϊ ας"ξ".

"μ- Laquinimod τεθπφιΰμ μδιεϊ θιτεμ ιιηεγι αξϊο γψκ δτδ μηεμιν αθψωϊ πτεφδ," ΰξψ ρεεο ΰπγψΰρεο, πωιΰ εξπλ"μ Active Biotech εδερισ λι Laquinimod ξιιφβϊ ΰαο γψκ αθιτεμ αηεμιν αθψωϊ πτεφδ ξΰηψ ωιρτχ μδν θιτεμ ιςιμ, αθεη εαγψκ ξϊο δξϊΰιξδ μθιτεμ ΰψεκ θεεη".

ΰεγεϊ δωμα δωπι απιρει δ-Laquinimod
ωμα IIb ωμ δπιρει ΰψκ 36 ωαεςεϊ, ελμμ ηεμι θψωϊ πτεφδ ωρψιχϊ MRI αξεην δψΰϊδ μτηεϊ πβς τςιμ ΰηγ. 102 ηεμιν ξϊελν παηψε αΰχψΰι μχαεφϊ αχψδ. 98 ηεμιν πθμε ξγι ιεν Laquinimod αξιπεο ωμ 0.3 ξ"β, ε-106 ηεμιν πθμε Laquinimod αξιπεο ωμ 0.6 ξ"β.

δπϊεπιν, ΰωψ δεφβε αξΰι δωπδ ατβιωδ δωπϊιϊ ωμ δΰχγξιδ δΰξψιχΰιϊ μπειψεμεβιδ ((AAN, δψΰε λι αχαεφϊ δηεμιν ΰωψ πθμδ Laquinimod αξιπεο ωμ 0.6 ξ"β πφτϊδ ιψιγδ ωμ 40% ατςιμεϊ δξημδ εραιμεϊ ψαδ μϊψετδ. λξε λο, πψΰϊδ ξβξδ ωμ δτηϊδ αωιςεψ δδϊχτιν, εβιγεμ αξρτψ δηεμιν ωμΰ ηεε δϊχτιν λμμ.

ωμα IIa ωμ δπιρει ΰψκ 24 ωαεςεϊ, αδεαμϊ ηαψϊ Active Biotech. αξδμλε δελη λι Laquinimod αξιπεο ιεξι ωμ 0.3 ξ"β, διπε αςμ ιλεμϊ ραιμεϊ θεαδ εΰσ δτηιϊ ΰϊ διεεφψεϊ δπβςιν δτςιμιν αξεην ωμ ηεμι θψωϊ πτεφδ αωμα δδϊχτι. αξρβψϊ πιρειι δωμα δωπι, δηεμιν δψΰε ραιμεϊ ψαδ μθιτεμ α-Laquinimod αξιπεο 0.3 ξ"β ε-0.6 ξ"β, τψθ μξρτψ ξχψιν ξζγξπιν ωμ ςμιιδ αΰπζιξι λαγ ωδιιϊδ ϊμειϊ-ξιπεο.

ΰεγεϊ θας
ηαψϊ θας ϊςωιεϊ τψξφαθιεϊ ας"ξ διπδ ηαψδ βμεαμιϊ ωαριρδ αιωψΰμ εΰηϊ ξ-20 δηαψεϊ δτψξφαθιεϊ δξεαιμεϊ αςεμν. θας ξϊξηδ αιιφεψ ϊψετεϊ βπψιεϊ ειιηεγιεϊ, αιιφεψ ηεξψιν τςιμιν μϊςωιιδ δτψξφαθιϊ εαιιφεψ ξεφψιν εεθψιπψιν, εδιπδ δηαψδ δξεαιμδ αςεμν αϊηεν δβπψιχδ. μθας ΰϊψι ιιφεψ, ξηχψ, ωιεεχ εδτφδ αιωψΰμ, αφτεο εαξψλζ ΰξψιχδ εαΰιψετδ. χψεα μ-90% ξξλιψεϊιδ ωμ δχαεφδ δο μφτεο ΰξψιχδ εμΰιψετδ.

ΰεγεϊ Active Biotech
ηαψϊ Active Biotech AB διπδ ηαψϊ αιεθλπεμεβιδ ωαριρδ αωαγιδ ξξεχγϊ ξηχψ ετιϊεη ωμ ξεφψι τψξφαθιχδ. μηαψδ τεψθτεμιε ςωιψ ωμ ξεφψιν ξτιϊεη ςφξι, ϊεκ δϊξχγεϊ αξημεϊ ΰεθΰιξεπιεϊ, αξημεϊ γμχϊιεϊ εαρψθο. ϊψετϊ δ-Laquinimod πηωαϊ λΰηγ ξδτψειχθιν δηωεαιν αιεϊψ ωμ δηαψδ.




Safe Harbor Statement under the U. S. Private Securities Litigation Reform Act of 1995: This release contains forward-looking statements, which express the current beliefs and expectations of management. Such statements are based on management’s current beliefs and expectations and involve a number of known and unknown risks and uncertainties that could cause Teva’s future results, performance or achievements to differ significantly from the results, performance or achievements expressed or implied by such forward-looking statements. Important factors that could cause or contribute to such differences include risks relating to Teva`s ability to successfully develop and commercialize additional pharmaceutical products, the introduction of competing generic equivalents, the competition from brand-name companies that are under increased pressure to counter generic products, or competitors that seek to delay the introduction of generic product, Teva's ability to generate revenues and profits closely tied to our success in obtaining U.S. market exclusivity for generic products, the impact of consolidation of our distributors and customers, regulatory changes that may prevent Teva from utilizing exclusivity periods, potential liability for sales of generic products prior to a final resolution of outstanding patent litigation, including that relating to the generic versions of Allegra®, Neurontin® and Wellbutrin XL® , the effects of competition on our innovative products, especially Copaxone® sales, the impact of pharmaceutical industry regulation and pending legislation that could affect the pharmaceutical industry, the difficulty of predicting U.S. Food and Drug Administration, European Medicines Agency and other regulatory authority approvals, the regulatory environment and changes in the health policies and structures of various countries, Teva’s ability to successfully identify, consummate and integrate acquisitions, potential exposure to product liability claims which are not covered by insurance, dependence on effectiveness of our patents and other protections for innovative products, significant operations worldwide that may be adversely affected by terrorism, political or economical instability or major hostilities, the difficulty of complex manufacturing of our products and supply delays, environmental risks, fluctuations in currency, exchange and interest rates, operating results and other factors that are discussed in Teva’s Annual Report on Form 20-F and its other filings with the U.S. Securities and Exchange Commission. Forward-looking statements speak only as of the date on which they are made and the Company undertakes no obligation to update or revise any forward-looking statement, whether as a result of new information, future events or otherwise.